Autoimmune Cytopenias

Immune Thrombocytopenic Purpura Complicated by Hepatitis C Virus–Related Membranoproliferative Glomerulonephritis After Rituximab Therapy

The authors describe the case of a 54-year-old Japanese man, diagnosed with ITP at 25 years of age, who presented with refractory ITP complicated by hepatitis C virus (HCV)-related membranoproliferative glomerulonephritis, which developed after rituximab therapy was initiated. They note that their case suggests “that HCV treatment should be prioritized over rituximab therapy for HCV-positive patients with ITP and that antiviral therapy for HCV may be effective for ITP itself.”

Internal Medicine