Autoimmune Cytopenias

Multicentric Castleman’s Disease in HIV patients: A Single-Center Cohort Diagnosed From 2008 to 2018

In a retrospective single-center study, researchers from University Hospital Düsseldorf at Heinrich Heine University in Germany describe their experience with HIV-associated MCD in patients admitted to the hospital between 2008 and 2018. “MCD,” they note, “is an important differential diagnosis to consider in HIV-infected patients, even in the era of effective cART [combination antiretroviral therapy].” Based on clinical outcomes observed for 9 patients, the investigators stated that ‘[t]he most effective first-line therapy and retreatment option remains rituximab.”