HER2-TARGETED THERAPIES

HER2+ Breast Cancer Treatment and Cardiotoxicity: Monitoring and Management

This comprehensive review analyses clinical trials of trastuzumab, lapatinib, pertuzumab, T-DM1, and neratinib in breast cancer. The authors discuss incidence and mechanisms for cardiotoxicity of HER2-targeted therapies, in addition to summarizing practices in management of cardiotoxicity for routine patient care.

Breast Cancer Research and Treatment