KINASE INHIBITORS

Cardiotoxicity of the BCR-ABL1 Tyrosine Kinase Inhibitors: Emphasis on Ponatinib

This review article explores the cardiovascular risks and mechanisms related to tyrosine kinase inhibitor therapy among patients with chronic myeloid leukemia, with a spotlight on ponatinib, including recent reported discoveries and future strategies for minimizing the CML-TKI–associated cardiotoxicities.

International Journal of Cardiology