Message from the Program Chair


SANDRA KURTIN

June 2021

SANDRA KURTIN, PhD, ANP-C, AOCN®

Nurse Practitioner
University of Arizona and University of Arizona Cancer Center

I hope everyone is enjoying the start of summer and perhaps even taking a break from busy work schedules. I hope you will take a few minutes to look at the newest content on Benign Hematology Updates.

Our Benign Hematology Basics 101 videos provide an overview of common and rare disorders.

The Autoimmune Cytopenias pillar updates this month include a report describing I-WISh, a large international survey of treatment perceptions related to immune thrombocytopenia (ITP), and a comprehensive review of novel emerging therapies for ITP and CLL-associated autoimmune hemolytic anemia.

The Bone Marrow Failure Disorders pillar offers information about a mechanism underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH); Marrowforums, a discussion and resource center for BMF patients and their healthcare providers; and the recent approval of the complement C3 inhibitor pegcetacoplan for treatment of PNH.

The Hemoglobinopathies pillar includes guidance on testing and follow-up to support early detection of hemoglobin disorders; and a study using a lifetime Markov model to assess the cost-effectiveness of a hypothetical cell or gene-therapy cure for sickle cell disease.

In Hereditary/Acquired Bleeding Disorders, recommendations to optimize testing for VWD during times of acute heavy menstrual bleeding and development of a risk score to predict high bleeding risk in low VWF patients are highlighted.

It’s an exciting time for patients with benign hematologic disorders, as new information about potential pathways and targets for treatment continues to emerge. Of course, connections to COVID-19 and hematologic malignancies still thread through the conversation. Please dive into the Benign Hematology Updates website. We will be adding new case studies and videos soon, so stay tuned!

SANDRA KURTIN

May 2021

SANDRA KURTIN, PhD, ANP-C, AOCN®

Nurse Practitioner
University of Arizona and University of Arizona Cancer Center

Greetings! I hope you’ve had an opportunity to explore JADPRO’s Benign Hematology Updates website, which launched in April. The site offers clinical pearls and learning opportunities in several formats, including important news and studies in the medical literature; useful resources and guidelines; and case studies and Fast Facts sheets that provide clinical snapshots of an array of benign hematologic disorders, with tips for management.

This month, we’re pleased to add video interviews that I conducted with the expert faculty editors for each of the four Class Categories: Jennifer Donkin offers “day in the life” insights into her work and resources for management of hemophilia and von Willebrand disease from childhood through adulthood; David Hughes and Frances Blevins discuss their collaboration in managing immune thrombocytopenia; Natasha Johnson highlights best practices in the management of paroxysmal nocturnal hemoglobinuria, or PNH; and Susan Carson focuses on what the advanced practitioner should keep front-of-mind when caring for patients with beta-thalassemia. A common theme in these videos is multidisciplinary management and coordination of care for patients with these often-chronic but rare disorders. 

As I noted in my welcome video, many of the disorders covered in this program are rare and less likely to be encountered in your clinical practice. However, I believe that information centered on the expanding and evolving management of benign hematologic disorders provides the advanced practitioner with myriad benefits—perhaps most notably a deepened understanding of how these disorders intersect with patient education and supportive care; malignant transformation; and, as we are learning, COVID-19.

Selected content is refreshed monthly, so please visit the Benign Hematology Updates website often and share the site with your colleagues. Take a moment to subscribe to the Journal of the Advanced Practitioner in Oncology (JADPRO) and join the Advanced Practitioner Society for Hematology and Oncology (APSHO) to get access to even more resources created expressly for advanced practitioners in oncology.

 

SANDRA KURTIN

April 2021

SANDRA KURTIN, PhD, ANP-C, AOCN®

Nurse Practitioner
University of Arizona and University of Arizona Cancer Center

Greetings, and welcome to JADPRO Benign Hematology Updates. I hope you will explore and engage with the full array of resources that we’ve developed for our advanced practitioner (AP) audience on management approaches to a broad range of disease states in the evolving field of benign blood disorders. APs play a critical role in the multidisciplinary care of these conditions—which can be inherited or acquired; chronic and mild or acute and life-threatening; are often rare; and may be challenging to diagnose. Comprehensive differential diagnosis is critical since the patients’ symptoms may be incorrectly attributed to inconsequential causes. These often-complex disorders may occur in conjunction with or as a result of cancer, and in some cases may transform into malignancies.

Complicating today’s management of benign hematologic disorders, of course, is the challenge of COVID-19, declared as a pandemic by the World Health Organization just a year ago, in March 2020. As we have learned, COVID-19 can manifest with acute vascular effects such as micro-occlusions, and “long haul” COVID survivors may experience key symptoms (such as chronic fatigue) that often manifest in our patients with blood disorders. Ongoing research and our own experience have shown that patients with inherited or acquired benign hematologic disorders are at increased risk of severe COVID-19. The impact of this emerging clinical challenge, which will likely continue in the near future even with ongoing rollout and uptake of the SARS-CoV-2 vaccine, will be explored in the current JADPRO Benign Hematology Updates program, which is planned to run through March 2022, with content refreshed regularly.

This comprehensive program is organized into four broad topic areas, each guided by a dedicated specialist or specialist team: Hereditary/Acquired Bleeding Disorders, led by Jennifer Donkin, PNP, DNP, from the Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles; Autoimmune Cytopenias, led by David Hughes, PharmD, BCOP, and Frances Blevins, PA-C, from Boston Medical Center; Hemoglobinopathies, led by Susan Carson, RN, MSN, CPNP, from the Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles; and Bone Marrow Failure Disorders, led by Natasha Johnson, MSN, APRN, AOCNP, from Moffitt Cancer Center.

This microsite offers a selection of important clinical studies and best-practice resources; my comprehensive Benign Hematology Basics presentation; Fast Facts, with essential information on current diagnosis, treatment, supportive care, and prognosis of selected benign blood disorders; case studies from practitioners working in a variety of clinical settings; and video discussions in which expert APs share their tips and perspectives on challenging aspects of care. The program faculty and I look forward to sharing our years of experience and practice pearls with you.

Learn more about our program launch, as well as other planned content for this special series, in my welcome video.

I look forward to sharing new content with you on a monthly basis, as we develop this expanding resource further. Please feel free to contact me via editor@advancedpractitioner.com with your comments and questions.