Hereditary/Acquired Bleeding Disorders
Case Studies
Section Editor
Jennifer Donkin, PNP, DNP
Children’s Hospital Los Angeles
Featured Case Study
Postpartum Bleeding in a G1P1 Female Carrier for Hemophilia A With Low Factor VIII Levels, and Care of Her Newborn With Severe Hemophilia A and Intracranial Hemorrhage
Presentation and History
The patient, a pregnant 22-year-old known carrier of hemophilia A at 37 weeks gestation, first presented to the emergency department (ED) of a hospital with a low baseline factor VIII level (21%; range of normal values: 50% to 150%) and symptoms of preeclampsia. This was her first pregnancy (G1P1), and she was carrying a male child.
Management of Thrombosis in a Patient With Antiphospholipid Antibody Syndrome
Presentation and History
The patient, a 26-year-old female, has antiphospholipid antibody syndrome (APS) and a history (in 2010) of unprovoked right femoral deep vein thrombosis (DVT) with slow resolution and with mild symptoms of post-thrombotic syndrome. APS, a systemic autoimmune disorder, is marked by recurrent arterial or venous thrombosis, sometimes with pregnancy morbidity, in the presence of persistent antiphospholipid autoantibodies.
Compartment Syndrome of the Hand in a Young Man With Severe Hemophilia A
Presentation
The patient, a 28-year-old male with severe hemophilia A, presents with numbness over several fingers of his left hand, including complete numbness of his left index finger, and bruising of the left palm (see Figures).
Diagnosis of von Willebrand Disease in a Young Woman With Easy Bruising and Heavy Menstrual Bleeding
Presentation
An 18-year-old woman presents with a referral from her primary care provider (PCP) for work-up for a possible bleeding disorder, due to a history of...
Meet the Faculty
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Hereditary/Acquired Bleeding Disorders Insights Into Hemophilia Treatment Trends: An Interview With Michelle L. Witkop, DNP, FNP-BC, From the National Hemophilia Foundation
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Hereditary/Acquired Bleeding Disorders Comprehensive Care of Patients With Hemophilia and von Willebrand Disease
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Hereditary/Acquired Bleeding Disorders Evaluating Women With Bleeding Disorders: An Interview With Jacquelyn Keegan, NP, From CHLA
